For more than ten years, the Brain Injury Research Center has focused on issues related to plasticity and recovery of function
following traumatic brain injury. Specifically, the Hovda laboratory has focused on the concept of metabolic dysfunction which is
related to the degree and extent that cells are in a state of energy crisis following injury. The reduction of the capability to produce
energy following general traumatic brain injury renders cells that survive the insult vulnerable to secondary injuries as well as
compromises their ability to express plasticity.
In addition, they have studied this phenomenon extensively in development, showing that not only is traumatic injury fundamentally
different between adult and developing brain, but it also carries with it a much greater cost for recovery.